Categorized as: Cure

Breakthrough Agreement Accelerates HIV Cure Research

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The International AIDS Society (IAS) announced on January 20, the finalization of a Common Material Transfer Agreement (cMTA) for the donation and use of antiretroviral drugs for pre-clinical studies in HIV cure research. This major achievement is the result of more than a year of negotiation with leading pharmaceutical companies. “This agreement will greatly accelerate the transfer of drugs for cure and remission studies,” said Nobel Laureate and Co-founder of the IAS Towards an HIV Cure initiative Françoise Barré-Sinoussi. “Many…

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Timothy Ray Brown: the accidental AIDS icon

Timothy Ray Brown, the first person cured of  HIV, is greeted by community members after a defeatHIV lecture at Seattle University in June 2013.  Photo by Bo Jungmayer / Fred Hutch News Service

The ‘Berlin patient’ didn’t ask to be cured of HIV; now he wants a cure for all Timothy Ray Brown became an icon the day he came out as the previously anonymous “Berlin patient” — the first and still only person in the world to be cured of the virus that causes AIDS. But the path to becoming the personification of hope for the 35 million people worldwide infected with HIV has been more challenging — and more convoluted — than many people realize. The…

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MHRP the U.S. Army medicine leads infectious disease and HIV vaccine research

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In 2004, U.S. Army Col. Jerome Kim, an infectious disease physician, flew to Bangkok to oversee a massive HIV vaccine study. It was the opportunity of a lifetime—and the stakes were high. If successful, it could be the first vaccine to show even moderate protection against HIV infection—a critical milestone in the fight against HIV. Sponsored by the U.S. Army in partnership with the government of Thailand, the Phase III clinical trial known as RV144 followed 16,000 Thai volunteers. The…

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amfAR’s $100M investment strategy aimed at curing HIV

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amfAR, The Foundation for AIDS Research, today announced that it has created a $100 million investment strategy in support of its Countdown to a Cure for AIDS initiative, launched last year with the aim of developing the scientific basis of a cure by 2020. The establishment of the amfAR Institute for HIV Cure Research within a major academic research institution with a grant of $20 million will be the centerpiece of the investment strategy. “This represents the greatest expansion of…

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Can AIDS Be Cured?

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One morning in the winter of 1981, my wife came home after her on-call shift at the U.C.L.A. Medical Center and told me about a baffling new case. Queenie was an eighteen-year-old prostitute, his hair dyed the color of brass. He had arrived at the emergency room with a high fever and a cough, and appeared to have a routine kind of pneumonia, readily treated with antibiotics. But the medical team retrieved a microbe from his lungs called Pneumocystis carinii….

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searcHIV Conversation About Curing HIV with Timothy Ray Brown and Dave Purdy

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A World AIDS Day Interview December 1, 2014 by MaryBeth Grewe of searcHIV Timothy Ray Brown is currently the only person considered to be cured of HIV and is the co-founder the Cure for AIDS Coalition with Dave Purdy. searcHIV had the opportunity to interview Timothy Ray Brown and Dave Purdy about their thoughts on HIV cure research and the founding of their organization. We are sharing it today in recognition of World AIDS Day 2014.  searcHIV:   Your organization, the…

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Have Doctors in Spain ‘Cured’ HIV patient with blood transplant?

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Spanish scientists are hopeful blood transplants from the umbilical cord of people with genetic resistance to HIV could provide a future treatment option in the battle against the Aids-causing virus after managing to ‘cure’ a patient in just three months. A 37-year-old man from Barcelona, who had been infected with the HIV virus in 2009, was cured of the condition after receiving a transplant of blood from such an umbilical cord. Unfortunately, the man died of cancer having developed lymphoma…

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How Did The Berlin Patient’ Become Cured Of HIV?

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Researchers are closer to unraveling the mystery of how Timothy Ray Brown, the only human cured of HIV, defeated the virus, according to a new study. Although the work doesn’t provide a definitive answer, it rules out one possible explanation. Brown remains one of the most studied cases in the HIV epidemic’s history. In 2006, after living with the virus for 11 years and controlling his infection with antiretroviral drugs, he learned that he had developed acute myeloid leukemia. (The…

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The Berlin Patient and the Mysterious Cure for HIV

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For Timothy Ray Brown, the past two decades have been characterized by extremes of bad and good fortune, a streak of adversity giving way to a stroke of incredible, impossible luck. In 1995, Brown, an American living in Berlin, was diagnosed with HIV. In 2006—having kept the virus in check for 11 years with antiretroviral drugs—he was diagnosed with another life-threatening illness: acute myeloid leukemia, a cancer that attacks the bone marrow and spreads to the blood. When radiation and…

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Only One Person Has Been Cured Of HIV, And Now A New Study Could Explain Why

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To this date, only one person is thought to have been cured of HIV — the “Berlin patient” Timothy Ray Brown. But no one is exactly sure which aspect of Brown’s treatment may have cured him. Now a new experiment on monkeys provides more evidence that a rare genetic mutation in the person who donated bone marrow to Brown may have had a central role in his cure. Brown’s HIV was eradicated in 2007 after he underwent a treatment in…

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