Categorized as: Reservoirs

Is Nano-Antiretroviral Therapy (Nano-ART) the Future of HIV Treatment?

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Nano-ART Experimental Combination Surprises with Anti-HIV Effectiveness A compound developed to protect the nervous system from HIV surprised researchers by augmenting the effectiveness of an investigational antiretroviral drug beyond anything expected. The potency of the combination treatment, tested so far in mice, suggests that it would be possible to rid the body of HIV for months, reducing the frequency with which patients must take these medications from daily to several times a year. Even when people with HIV infection take…

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Biologist’s Work on ‘Viral Reservoirs’ May Have Impact on AIDS/HIV

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A drug used to treat patients with multiple sclerosis and Crohn’s disease has confirmed how “viral reservoirs” form in patients living with HIV and AIDS and also proven effective in animal trials at blocking the pathways to those reservoirs in the brain and gut, according to new research conducted by Professor of Biology Ken Williams and colleagues from other universities. The drug, a humanized antibody called natalizumab, is produced by Biogen Idec Inc. under the brand name Tysabri and prescribed…

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Immune cells proposed as HIV hideout don’t last in primate model

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Where does HIV hide? Antiretroviral drugs can usually control the virus, but can’t completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well. New research from Yerkes National Primate Research Center, Emory University, sheds light on the question of which cells support viral replication and persistence, and the answers have…

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