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Path to a Cure? A protein in humans and other primates switches on immune system, stops HIV infection

TRIM5alpha protein HIV treatment

An new HIV cure path may now be possible. A new study published in the journal Heliyon, has provided amazing insights into finding a cure for HIV. Scientists have uncovered part of a protein, found in humans as well as other primates that can turn on the immune system and fight off HIV at the same time. The findings are big enough to be used in developing anti-HIV gene therapy, researchers suggest. The TRIM5alpha protein has the power to intercept…

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Charlie Sheen: “If there is one guy on this planet that’s going to deliver a cure, It’s me.”

Charlie Sheen HIV positive and Cure

“If there is one guy on this planet to contract this, that’s going to deliver a cure, It’s me. It’s me. Seriously. Seriously.”                                 – Charlie Sheen, Today Show Exclusive Interview, November 17, 2015   Charlie Sheen revealed he is HIV positive Tuesday in an exclusive TODAY interview with Matt Lauer.  “It’s a hard three letters to absorb. It’s a turning point in one’s life,” the 50-year-old actor said. Sheen said he made the announcement to end a smear campaign…

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What Is It Like to Be Cured of AIDS? A Conversation With the Berlin Patient


Interview and Portraits by Daniel Jack Lyons for the Huffington Post on November 13, 2015 When Timothy Ray Brown underwent a bone marrow transplant in Berlin during the winter of 2007, he was unaware of the historical significance that the surgery would later have. He hoped that the grueling procedure would free him from Leukemia, and he knew there was an unlikely chance that he could also be rid of HIV. Eight years later, Brown remains free from Leukemia and…

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Vice on HBO Special Report: The Fight to End AIDS


Countdown to Zero is a VICE on HBO special report on the fight to end AIDS.  It will focusing on the breakthroughs in cure, prevention and treatment including finding a cure.  The documentary is currently airing on HBO and had its World Premiere on Tuesday, December 1, (World AIDS Day). Learn more by going to VICE on HBO by clicking here. The special, hosted by VICE founders and correspondents Shane Smith and Suroosh Alvi, goes inside the search for a…

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Tale of Two Diagnoses: For seven months, Gary Steinkohl believed he was cured


For seven months, Gary Steinkohl believed he was cured of HIV. Appeared in POZ Magazine, by Casey Halter on November 3, 2015 In July 2012, the world was told that two HIV-positive men with lymphoma, who had recently undergone chemotherapy and stem cell transplants, had stopped taking their antiretroviral medications and for months showed no signs of HIV in their blood. The findings—which were presented in Kuala Lumpur at the 7th International AIDS Society Conference from a study led by…

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World’s First Patient Cured Of HIV Remains A Tantalizing Exception To The Rule


The procedure was harrowing, involving multiple rounds of chemotherapy, followed by radiation. He came down with graft vs. host disease and had to have a whole second transplant. But in the end, Timothy Ray Brown became the first person in the world functionally cured of HIV.  The announcement that someone had been cured of this hitherto incurable disease thrilled scientists, patients and activists. Interview of Timothy Ray Brown and Keith Jerome, MD on NPR radio KPLU interview By Gabriel Spitzer…

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Madame Peng Liyuan, first lady of China, visits Fred Hutch Vaccines


Bill and Melinda Gates, Nobel-winner Dr. Linda Buck among luminaries meeting and touring Hutch HIV vaccine lab Sept. 23, 2015 -By Linda Dahlstrom / Fred Hutch News Service She is a renowned opera and folk singer. She’s a champion of education for women, particularly in rural areas of China like the one she grew up in as the daughter of a night school principal. She’s a civilian in the People’s Liberation Army, holding a rank equivalent to major general. But…

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Getting to Zero: Are We Close to a Cure for AIDS?


San Francisco pushes early HIV treatment—with an eye toward HIV Cure. Appeared in Pacific Standard, written by Rob Waters on Aug 17, 2015   When Esteban got a call from his ex-lover last May advising him to get tested for HIV because he’d been exposed to the virus, Esteban acted quickly and made an appointment at Magnet, a testing site in San Francisco’s Castro district. He went in on a Wednesday at 2 p.m. and a nurse drew his blood….

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HIV Cure: From pipe dream to promising


A longtime activist offers cautious optimism on the eve of HIV cure conference At the second annual Conference on Cell and Gene Therapy for HIV Cure at Fred Hutchinson Cancer Research Center, researchers and activists offer cautious optimism for a cure (of some kind) in the not-too-distant future. By Mary Engel / Fred Hutch News Service   Recently, Jeff Sheehy — a longtime gay civil rights and HIV/AIDS activist in San Francisco — had a conversation with a 23-year-old man…

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Aggressive new HIV strain detected in Cuba


A new HIV strain in some patients in Cuba appears to be much more aggressive and can develop into AIDS within three years of infection. Researchers said the progression happens so fast that treatment with antiretroviral drugs may come too late. Without treatment, HIV infection usually takes 5 to 10 years to turn into AIDS, according to Anne-Mieke Vandamme, a medical professor at Belgium’s University of Leuven. According to the study, published in the journal EBioMedicine, Vandamme was alerted to…

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